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Leukemia Research Foundation: Advancing Leukemia Research and Support

Dated: December 19, 2025

Introduction – Overview of the Leukemia Research Foundation

The Leukemia Research Foundation is a leading nonprofit organization dedicated exclusively to funding leukemia research and supporting patients and families affected by this group of blood cancers. Established in 1946 in Chicago, Illinois, the Foundation was created to honor the memory of 12-year-old Sherwin Pessin and to drive research efforts toward understanding and curing leukemia. Since its inception, the Foundation has raised nearly $100 million in support of its mission and has become one of the most prominent leukemia research funders worldwide.

History and Background

  • Founding and Early Years
    • The Leukemia Research Foundation was founded in 1946 during a time when leukemia was poorly understood and treatments were extremely limited. Motivated by a personal loss, the founders aimed to create a lasting impact by investing in scientific research that could improve patient outcomes and one day lead to a cure.
  • Evolution Over Time
    • Over the decades, the Foundation has evolved into the nation’s largest nonprofit focused exclusively on leukemia research, funding projects across the United States and worldwide. It has adapted to advances in medical science while maintaining its original goal of supporting pioneering research and patient care.

Mission and Purpose

  • Cure Through Research
    • The core mission of the Leukemia Research Foundation is to cure leukemia by funding innovative basic and translational research. This mission encompasses:
      • Accelerating the development of new treatments and therapies
      • Supporting studies that deepen scientific understanding of leukemia’s causes and mechanisms
      • Investing in projects that have the potential to transform clinical care and patient survival outcomes.
  • Supporting Patients and Families
    • Beyond research, the Foundation’s purpose includes helping patients and their families through support programs, educational resources, and financial assistance designed to improve quality of life during treatment and recovery.

Governance and Structure

  • Nonprofit and Tax-Exempt Organization
    • The Leukemia Research Foundation is a tax-exempt nonprofit organization headquartered in Northfield, Illinois. It is governed by a Board of Directors, supported by volunteer chapters, and guided by a Medical Advisory Board that ensures the scientific rigor and clinical relevance of funded research.
  • Accountability and Transparency
    • The Foundation’s governance structure emphasizes financial transparency and accountability. It has repeatedly earned high ratings from independent charity evaluators such as Charity Navigator, where it has received four-star ratings for its financial health, accountability, and transparency, reflecting prudent stewardship of donor funds.

Funding and Grants

  • Research Grants
    • A cornerstone of the Foundation’s activities is its grant programs, which support researchers at various stages of their careers. The flagship New Investigator Research Grant Program awards grants of up to $150,000 over two years to early-career investigators pursuing innovative leukemia research projects.
  • Grant Review Process
    • Grants are selected through a rigorous, peer-reviewed application process guided by national and international research experts to ensure that funding goes to projects with high scientific potential.
  • Support for Infrastructure and Collaboration
    • In addition to investigator-initiated research awards, the Foundation supports collaborative initiatives with complementary organizations and other funding entities to broaden the impact of its investment in leukemia science.

Major Programs and Initiatives

  • New Investigator Research Grant Program
    • This program is the Foundation’s flagship initiative, designed to empower early-career scientists tackling innovative research that could lead to breakthroughs in leukemia treatment and understanding. Awards are intentionally targeted to support the next generation of leaders in blood cancer science.
  • Annual Education and Patient Support Programs
    • The Foundation also organizes virtual education series, webinars, and patient support events to provide up-to-date clinical insights and treatment information for patients, caregivers, and families.
  • Fundraising Events and Community Engagement
    • Through annual events such as runs, walks, and community fundraisers, the Foundation mobilizes public support and builds donor communities invested in its mission.

Impact and Examples of Work Funded

  • Global Research Investments
    • To date, the Leukemia Research Foundation has funded more than 750 research projects worldwide, spanning a wide range of topics in leukemia biology, treatment development, immunotherapy, and more.
  • Scientific Breakthroughs
    • Projects funded by the Foundation have contributed to discoveries such as new targeted therapies for acute leukemia and insights into how dietary factors may influence leukemia progression, showcasing the diverse impact of its research portfolio.
  • Patient and Family Support Outcomes
    • The Foundation has disbursed millions in need-based financial support, helped thousands participate in educational programs, and offered resources that empower patients and caregivers throughout the cancer journey.

Conclusion – Advancing Science and Supporting Lives

The Leukemia Research Foundation stands as a vital force in the fight against leukemia, uniquely focused on both research funding and patient-centered support. From its beginnings in 1946 to its current global reach, the Foundation has remained committed to accelerating scientific discovery and improving the lives of patients and families affected by leukemia. Its continued work promises to bring ever-closer the ultimate goal of curing leukemia for future generations.

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